1986年Graven等人报道了许多滥用胃肠外给药,引起G组链球菌(GGS)菌血症的流行病学特点和临床表现。我们想简略地报道一下,在纽约的Bellevue医院里,同样病人的情况及治疗此病的经验。1981年1月至1986年3月,从我们微生物实验室观察记录中,鉴定出45例GGS菌血症患者。在36份有价值的医学记录资料中,发现16人在入院时,曾经积极的滥用非肠道给药。16名病人的平均年龄为36.8岁(范围在24—54岁),入院前胃肠外滥用药的平均时间为14年(1—30年)。其中8名病人,占50%的病例,在新近药物注射部位有蜂窝组织炎或其它软组织感染征象。有8名病人诊断为心内膜炎,这8名病人均有发热,心脏杂音,血沉增快,重度菌血症。并用超声心动图观察了病情发展。抗生素敏感试验(稀释法和圆盘播散法)对11种抗生素均有效。所有的病人对青霉素,氨苄青霉素,先锋霉素,万古霉素都敏感,对四环素抗 In 1986, Graven et al. Reported a number of epidemiological features and clinical manifestations of abusing parenteral administration causing the group G Streptococcus (GGS) bacteremia. We would like to briefly report on the same patient’s condition and experience in the treatment of the disease at Bellevue Hospital in New York. From January 1981 to March 1986, 45 patients with GGS bacteremia were identified from our microbiological laboratory observations. Of the 36 valuable medical records, 16 were found to have actively abused parenteral medication at admission. The average age of 16 patients was 36.8 years (range 24-54 years), and the average time for parenteral abuse prior to admission was 14 years (1-30 years). Eight of these patients, accounting for 50% of cases, had signs of cellulitis or other soft tissue infections at the site of recent drug injections. There are 8 patients diagnosed as endocarditis, these eight patients have fever, heart murmur, ESR, severe bacteremia. Echocardiography was used to observe the progression of the disease. Antibiotic sensitivity tests (dilution and disk dissemination) are effective on all 11 antibiotics. All patients were sensitive to penicillin, ampicillin, cephalosporins, vancomycin, tetracycline resistance