难治性恶性实体瘤采用大剂量化疗可获得常规剂量化疗难以达到的效果,为保证大剂量化疗的安全实施,必须有效保护造血。我院自1997年1月至今,采用自体外周血干细胞移植(APBSCT)支持大剂量化疗成功治疗3例实体瘤患者。现报告如下。病例报告例一,男25岁,因“纵隔精原细胞瘤锁骨上, The use of high-dose chemotherapy for refractory malignant solid tumors can achieve the effect that conventional dose chemotherapy can not achieve. In order to ensure the safe implementation of high-dose chemotherapy, it is necessary to effectively protect hematopoiesis. Since January 1997, our hospital has used autologous peripheral blood stem cell transplantation (APBSCT) to support the successful treatment of 3 solid tumor patients with high-dose chemotherapy. The report is as follows. Case report case 1, male 25 years old, due to "mediastinal seminoma, supraclavicular,