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目的对某三级医院围手术期抗菌药物的使用情况进行合理性判断与分析。方法从医院2013年1月-2014年9月的出院病历中抽取180份手术病例,以卫生部《抗菌药物临床应用指导原则》为判断标准,对围术期抗菌药物的使用率,用药时间、用药疗程,药物选择及用法用量等相关指标进行综合评价。结果Ⅰ类切口手术预防性抗菌药物使用率为54.14%,术前用药时间的正确率达87.50%;Ⅱ类切口手术预防性抗菌药物使用率为43.24%,术前用药时间的正确率为32.43%。各类切口术后用药疗程普遍较长。在抗菌药物的选择及用法用量方面较为合理。结论围术期抗菌药物使用存在不合理情况,需加以改进。
Objective To evaluate the rationality of perioperative antibacterials usage in a tertiary hospital. Methods A total of 180 surgical cases were collected from the hospital medical records from January 2013 to September 2014. According to the “Guiding Principles for Antibacterials Clinical Application” of the Ministry of Health as the standard of judgment, the utilization rate of antibacterials during perioperative period, Medication course, drug selection and usage and other related indicators for comprehensive evaluation. Results The preventive antibacterials utilization rate was 54.14% in type Ⅰ incision operation, the correct rate of preoperative medication time was 87.50%. The preventive antibacterial drug usage rate in type Ⅱ incision operation was 43.24% and the correct preoperative medication time was 32.43% . Various types of incision medication generally longer. In the choice of antimicrobial agents and the amount of usage is more reasonable. Conclusion Perioperative use of antimicrobial drugs unreasonable, need to be improved.