关于幽门螺杆菌(Hp)感染,有观点认为Hp直接干扰代谢或间接慢性炎症作用可与多种疾病相关,甚至提出Hp或Hp的某些蛋白成分可作为治疗一些疾病如哮喘、肥胖等方法。但是,对于胃食管反流病、免疫异常疾病(如哮喘、食物过敏、炎症性肠病)和肥胖等现有资料研究发现,没有证据证明Hp对人体的“有益性”。所以,对于Hp感染相关性疾病需积极予以根治,并加强研究,应对日益上升的Hp耐药性和治疗失败率。 Regarding Helicobacter pylori (Hp) infection, it is thought that the direct interference with metabolism of Hp or the indirect chronic inflammation may be related to various diseases. Some protein components of Hp or Hp are even proposed as a method for treating diseases such as asthma and obesity. However, there is no evidence to prove that Hp is “beneficial to the human body” based on available data such as gastroesophageal reflux disease, abnormal immune diseases such as asthma, food allergy, inflammatory bowel disease and obesity. Therefore, the Hp infection-related diseases need to be actively eradicated and to strengthen research to deal with the rising incidence of Hp resistance and treatment failure.