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1944年链霉素的发现给结核病的治疗学带来了新的希望。后来陆续发现了对氨柳酸钠,异菸肼,异菸腙等药,更进一步加强抗痨药物的临床疗效。但是不久临床及实验医学都发现也证实了结核菌对这些药物可以发生耐药性或抗药性,影响临床的治疗效果,引起了许多医务人员及病人的顾虑及失望。近几年来关于结核菌耐药性问题,国内外有不少的研究和临床
The discovery of streptomycin in 1944 brought new hope for the treatment of tuberculosis. Later, one after another on the sodium salicylate, isoniazid, isoniazid and other drugs, and further enhance the clinical efficacy of anti-tuberculosis drugs. However, shortly afterwards, both clinical and laboratory medicine have also confirmed that M. tuberculosis can develop drug resistance or resistance to these drugs and affect clinical treatment effects, causing concern and disappointment to many medical personnel and patients. In recent years on the issue of drug resistance in tuberculosis, there are many domestic and foreign research and clinical