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目的 :研制双氯芬酸钾的缓释微丸并建立含量测定的方法。方法 :在含有主药的丸心外包控释膜 ,控制药物的释放速度。结果 :获得了释药时间持续 8小时的缓释微丸。结论 :采用缓释微丸剂型 ,可使药物达到速效和缓释的作用。
Objective: To develop diclofenac potassium sustained-release pellets and to establish a method for determination of content. Methods: The pill containing the main drug core control release film, control the release rate of the drug. RESULTS: Sustained-release pellets with sustained release for 8 hours were obtained. Conclusion: The use of sustained-release pellets form, the drug can achieve rapid and sustained release effect.