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本文观察了102名新生儿出生后至18月龄的HBV血清学指标的动态变化,婴儿分成乙型肝炎疫苗按种组(63人)和对照组(39人), 观察期间HBsAg始终阴性的70名婴儿,出生后6、12和18月龄的抗-HBc阳性率依次为90％、30％和4.3％;而HBsAg阳转的27名婴儿,18月龄时抗-HBc全都阳性,但仅有6名婴儿在6月龄时测出IgM抗-HBc,疫苗接种组婴儿出生后1、3、6、12和18月龄的抗-HBs阳性率,依次为28.6％、76.2％、77。8％、82.5％和82.5％;对照组婴儿18月龄时抗-HBs阳性率仅为12.8％。
In this paper, the dynamic changes of HBV serology in 102 newborns from birth to 18 months of age were observed. The infants were divided into hepatitis B vaccine group (63) and control group (39). During the observation period, HBsAg was always negative Among the infants, the positive rates of anti-HBc at 6, 12 and 18 months after birth were 90%, 30% and 4.3%, respectively. In contrast, 27 infants with positive HBsAg were all positive at 18 months of age but only anti-HBc at 18 months Six infants detected IgM anti-HBc at 6 months of age. The positive rates of anti-HBs in infants at 1, 3, 6, 12 and 18 months after birth were 28.6%, 76.2%, 77, respectively. 8%, 82.5% and 82.5% respectively. The positive rate of anti-HBs in control group was only 12.8% at 18 months of age.