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研究目的探讨藻酸双酯钠(PSS)治疗慢性肺心病的临床效果。研究背景1986年PSS问世以来,已被广泛用于治疗缺血性脑病、心血管疾病的防治。但用于治疗慢性肺心病的文献报道尚少。方法用血粘度计、血小板聚集计、硫酸钠沉淀双缩脲显色法和温由伯法测定了50例(治疗组)慢性肺心病患者的全血比粘度、血浆比粘度、血小板血红蛋白和纤维蛋白原。并与45例(对照组)作比较。结果治疗组的全血比粘度、血浆比粘度、血小板和纤维蛋白原与对照组相比均有明显下降(P<0.05)、临床有效率94%,对照组有效率77.8%(P<0.05)。结论PSS对慢性肺心病急性期的疗效肯定,安全可靠。
Objective To investigate the clinical effect of sodium alginate (PSS) in the treatment of chronic pulmonary heart disease. Background of the research Since the advent of PSS in 1986, it has been widely used in the treatment of ischemic encephalopathy and cardiovascular disease. However, the literature for the treatment of chronic pulmonary heart disease is still low. Methods The blood viscosity, plasma specific viscosity, platelet hemoglobin and fiber in 50 patients with chronic cor pulmonale were measured by blood viscosity meter, platelet aggregation meter, sodium sulphate precipitation biuret colorimetry and Wen Yubu method Proteins. And compared with 45 cases (control group). Results Compared with the control group, the whole blood viscosity, plasma specific viscosity, platelet and fibrinogen in the treatment group were significantly decreased (P <0.05), the clinical effective rate was 94% and the control group was 77.8% (P <0.05) . Conclusion The efficacy of PSS in the acute phase of chronic pulmonary heart disease is definite, safe and reliable.