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β-阻滞剂对实验性冠状动脉闭塞和急性心肌梗塞的有益作用已被证实.然而,在心肌梗塞后6～24小时内开始使用β-阻滞剂能否预防或减少梗塞的扩展,尚属疑问.本文旨在测定梗塞后24小时内开始给予β-阻滞剂醋丁酰心安对未并发心力衰竭的急性透壁性前壁心肌梗塞患者梗塞范围扩展和心肌功能的影响.方法:26例急性透壁性前壁心肌梗塞者,随机分成二组:A组12人,年龄29～61岁(平均52岁),仅用肝素治疗,作为对照;B组14人,年龄31～63岁(平均51岁),除肝素外,在起病24小时内用醋丁酰心安(Acebutolol)1毫克/公斤体重滴注,同时监
The beneficial effects of β-blockers on experimental coronary occlusion and acute myocardial infarction have been demonstrated, however, whether β-blockers can be prevented or reduced within 6 to 24 hours after myocardial infarction has been demonstrated Is a matter of doubt.The purpose of this paper is to determine the effect of starting beta-blocker, butbofibrate, on infarct size expansion and myocardial function in patients with acute transmural anterior wall myocardial infarction without heart failure within 24 hours after infarction.Methods: Cases of acute transmural anterior myocardial infarction were randomly divided into two groups: A group of 12 patients, aged 29 to 61 years (mean 52 years), only heparin treatment, as a control; B group of 14 people, aged 31 to 63 years (Mean 51 years). In addition to heparin, instillation of Acebutolol 1 mg / kg body weight within 24 hours of onset,