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目的探讨卵巢恶性生殖细胞肿瘤保留生育功能治疗对患者生存情况、月经和生育功能的影响。方法回顾性分析21例保留生育功能的卵巢恶性生殖细胞肿瘤年轻患者的生存情况及生育情况,包括治疗前后月经的变化及孕产情况等。结果截止到2008年8月30日,21例患者中,有2例死亡,19例存活,总体生存率为90.5%。化疗期间4例月经紊乱,化疗后3个月左右均恢复正常。6例有生育愿望,共孕6次,足月产4次,流产2次。结论保留生育功能的手术对有生育要求的患者是可行的。
Objective To investigate the effect of preserving reproductive function of ovarian malignant germ cell tumor on survival, menstruation and reproductive function in patients with malignant ovarian germ cells. Methods Retrospective analysis of 21 cases of ovarian malignant germ cell tumor retain reproductive function in young patients with survival and fertility, including changes in menstruation before and after treatment and pregnancy status. Results As of August 30, 2008, 21 of 21 patients died and 19 survived with an overall survival of 90.5%. 4 cases of menstrual disorders during chemotherapy, 3 months after chemotherapy were returned to normal. Six cases of childbirth desire, a total of 6 pregnant, full-term 4 times, abortion 2 times. Conclusion Retention of fertility surgery is feasible for patients with fertility requirements.