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作者于1981年6月对哈尔滨市3200名中小学生进行血红蛋白普查时,发现一例α链慢泳异常血红蛋白,经化学结构分析证明这种异常血红蛋白为HbG-Chinese(α_2~(30)α_2~(30[Bll]Glu→Gln)β_2)。本文报导其化学结构分析结果。材料和方法一、临床资料先证者徐×,男性,12岁,汉族,小学生。籍贯:父天津市,母黑龙江省。体检未发现皮肤苍白与巩膜黄染等贫血体征,肝脾未触及。红细胞形态无异常,网织细胞0.2%。17%异丙醇试验阴性,热变性试验0.7%,镰变试验阴性,说明这种血红蛋白非属不稳定血红蛋白。抗碱血红蛋白含量0.93%,HbA_2含
When the hemoglobin census was conducted on 3200 primary and middle school students in Harbin in June 1981, we found a case of abnormal hemoglobin of α-chain slow swimming. The chemical structure analysis showed that this abnormal hemoglobin is HbG-α (α_2 ~ (30) α_2 ~ (30 [B11] Glu → Gln) β_2). This article reports the results of its chemical structure analysis. Materials and methods First, clinical information Proof Xu ×, male, 12 years old, Han nationality, primary school students. Birthplace: Father Tianjin City, the mother of Heilongjiang Province. Physical examination showed no signs of anemia such as pale skin and scleral yellow dye, liver and spleen not touched. No abnormal erythrocyte morphology, reticulocytes 0.2%. 17% isopropanol test negative, thermal denaturation test 0.7%, sickle change test negative, indicating that this hemoglobin is not stable hemoglobin. Anti-alkali hemoglobin content of 0.93%, HbA_2 containing