The synthesis of sequence controlled polymers received increasing interest in polymer science. This mini review focuses on the principle and methods developed to control the sequence in polymer products from various polymerization mechanisms and processes. Typical examples are discussed to explicate the progress in this research field. This synthesis of sequence controlled polymers received increasing interest in polymer science. This mini review focuses on the principle and methods developed to control the sequence in polymer products from various polymerization mechanisms and processes. Typical examples are discussed to explicate the progress in this research field.