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目的 通过对来自于寨卡病毒流行区的入境人员进行追踪和筛查,发现寨卡病毒感染者,对其进行隔离,以期防止寨卡病毒病的本地化流行.方法 江门恩平市(县)对2016年2月28日至7月15日来自于委内瑞拉、哥斯达黎加等国家的1 141例入境人员进行健康随访,并对725例进行了流行病学调查,并采集血液、唾液或尿液,采用RT-PCR法检测寨卡病毒核酸,筛查出寨卡病毒感染者.结果 通过主动追踪和筛查,从725例中查出8例寨卡病毒病患者和3例隐性感染者,检出阳性率为1.52％.其中男性检测423例,阳性4例;女性检测302例,阳性7例,男女感染率相近,差异无统计学意义(x2 =2.22,P＞0.05).73.33％的感染者通过主动监测被检出,开展该项工作4个月来无本地病例出现.结论 对寨卡流行区入境人员进行主动追踪和筛查,是防控寨卡病毒病本土化流行的有效措施之一.“,”Objective To actively monitor passengers coming from Zika virus endemic regions and screen for Zika virus infection to prevent the native spread of the disease.Methods A total of 1141 inbound passen gers who came from Venezuela and other south American countries from Februray 28 to July 15,2016 were monitored and an epidemiological survey was conducted among 725 passengers whose blood,saliva and urine samples were collected for the detection of nucleic acid of Zika virus by RT-PCR.Results By active surveillance and screening,eight patients with Zika disease and three silent virus carriers were found with the positive rate of 1.52 ％.There was no significant difference of detection rate between male and female passengers (x2 =2.22,P＞0.05).73.33％ of infected passengers were recognized by active surveillance.No local cases appeared during the four months active surveillance period.Conclusions Active surveillance is one of the most effective ways to prevent the local spread of Zika virus.