抗病毒化疗开始于五十年代初期,但迄今进展缓慢。控制病毒感染的一条成功途径是研制疫苗,例如天花、脊髓灰白质炎、风疹疫苗等。但与病毒性疾病有关的200多种病毒都搞疫苗实际上不可能,因此有必要研究抗病毒化疗药物。病毒是以核酸为中心、以蛋白质为外壳组成的微小颗粒,它须寄生于活细胞内,利用宿主细胞或病毒诱导的酶系合成核酸和蛋白质,进行复制、增殖。这样,造成抗 Antiviral chemotherapy started in the early 1950s, but so far has been slow. One of the successful ways to control the virus infection is to develop vaccines such as smallpox, polio and rubella vaccines. However, it is practically impossible for more than 200 kinds of viruses associated with viral diseases to be vaccines. Therefore, it is necessary to study anti-viral chemotherapy drugs. Virus is a nucleic acid-centered, protein shell composed of tiny particles, which must be parasitic in living cells, the use of host cells or virus-induced enzyme synthesis of nucleic acids and proteins, replication, proliferation. In this way, cause resistance