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探讨急性重复缺氧对人脑功能的影响程度,为高原脑功能研究积累借鉴资料。随机选择常年频繁出入海拔3000-5400m的某部汽车兵50名(急性重复缺氧组)及驻守海拔3700m与5380m1年的40名健康青年,采用韦氏成人智力量表(WAIS—RC)简式四合一及韦氏记忆量表甲式(WMS)现场进行智力与记忆功能的心理测验,并设置平原对照组。结果:急性重复缺氧组与平原对照组(海拔1400m)、高原甲组(海拔3700m移居1年)及高原乙组(海拔5380m移居1年)比较,VIQ(语言)PIQ(操作)FIQ(智商)均无显著性差异(P>0.05);急性重复缺氧组的记忆功能与平原对照组比较,1-100、积累、记图、再认、再生、联想、触摸得分降低非常显著(P<0.01),与高原甲组比较,1-100、再认、触摸降低非常显著(P<0.01),再生、理解、MQ(记忆商数)得分显著增高(P<0.01或P<0.05)。与高原乙组比较,1—100、再认、触摸、降低非常显著(P<0.01),100-1、理解、背数、MQ得分显著增高(P<0.01或P<0.05)。结论:急性重复缺氧机体产生间歇性的低氧适应,脑功能较不同程度的持续性缺氧损害轻,但记忆功能仍低于平原正常人水平。
Explore the impact of acute repeated hypoxia on human brain function, accumulation of reference data for the study of plateau brain function. Forty healthy young men (50 acute ambient hypoxia group) and 37 healthy volunteers (5380m1 altitude) stationed at frequent altitudes of 3000-5400m were randomly selected using WAIS-RC Four in One and Wechsler memory scale A (WMS) on-site intelligence and memory function of psychological tests, and set the plain control group. RESULTS: Compared with the control group (1400 m altitude), the plateau group A (3700 m above sea level) and the plateau group B (1 year after the elevation of 5380 m), the VIQ (language) PIQ (operation) FIQ ) Had no significant difference (P> 0.05). Compared with control group, the memory function of acute repeated hypoxia group was very significant (1-100), accumulated, recorded, recognized, regenerated, (P <0.01). Compared with plateau group A, the scores of 1-100, then recognized and touch decreased significantly (P <0.01). 01 or P <0.05). Compared with plateau group B, the scores of 1-100, recognition, touch and decrease were significantly (P <0.01), and the scores of 100-1, understanding, back number and MQ were significantly increased (P <0.01 or P <0. 05). CONCLUSION: Acute hypoxic hypoxia produces intermittent hypoxic adaptation. Compared with different degrees of persistent hypoxia, brain function is mild, but memory function is still lower than that of plain normal subjects.