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目的:观察降纤酶治疗脑梗塞的疗效和安全性.方法:60例脑梗塞患者随机分为两组,其中30例作为治疗组给予降纤酶及扩血药物治疗,对照组30例给予扩血药物治疗.在治疗3W后对患者神经功能缺损进行评分,并对比两组疗效及治疗前后的血液流交学变化,观察用药后的副作用.结果:治疗组总有效率96.7%;明显优于对照组60%(P<0.01),且血液流变学变化显著,无不良反应.结论:降纤酶对于脑梗塞的治疗是安全而有效的。
Objective: To observe the efficacy and safety of defibrase in the treatment of cerebral infarction. Methods: Sixty patients with cerebral infarction were randomly divided into two groups, of which 30 patients were treated with defibrase and vasodilator as the treatment group and 30 patients in the control group were treated with vasodilator drugs. After 3 weeks of treatment, the neurological deficits of patients were scored, and the curative effect and blood flow changes before and after treatment were compared. The side effects after treatment were observed. Results: The total effective rate was 96.7% in the treatment group, which was significantly better than 60% in the control group (P <0.01). Hemorheology changed significantly with no adverse reactions. Conclusion: Defibrase is safe and effective for the treatment of cerebral infarction.