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作者把乌干达某地居民分为两组,实验组是脾脏中度或高度肿大者;对照组是脾脏未能触及或轻变肿大者。两组同时测定血清中IgG及IgM的含量,并用纯IgG与纯IgM制成的萤光标记抗体,测定2组居民血清对恶性疟原虫及三日疟原虫的滴度。调查结果,两组居民血清中IgG的含量和对2种疟原虫的抗体滴度都无明显差别,但IgM的含量及其对恶性疟原虫的抗体滴度,巨脾组都明显高于对照组。作者认为热带巨脾症患者的疟疾抗体滴度高于无脾肿者早已为前人所证实,巨脾症
The author divided the inhabitants of a certain place in Uganda into two groups. The experimental group was moderate or highly enlarged spleen; in the control group, the spleen failed to reach or swollen enlarged. Serum IgG and IgM levels were determined simultaneously in both groups. Fluorescently labeled antibodies were also prepared using pure IgG and pure IgM. Titers of serum from two groups of patients against P. falciparum and Plasmodium malariae were determined. The results of the two groups of residents in serum IgG levels and two kinds of Plasmodium antibody titers no significant difference, but the content of IgM and its antibody against Plasmodium falciparum, splenomegaly group were significantly higher than the control group . The authors believe that patients with tropical splenic mastitis antibody titers higher than those without splenomegalosis has been confirmed for the predecessors, splenomegaly