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目的探讨皮肌炎患者合并感染的特点及相关危险因素。方法回顾性分析107例患者的临床资料和感染情况,并填入自制表格,内容包括性别、年龄、住院时间、患者的感染率、感染部位、基础疾病、病原菌等,并采用流行病学方法进行统计分析。结果皮肌炎患者发生医院感染41例,感染率38.32%,感染部位以呼吸道居多,占41.46%,其次为皮肤粘膜感染,占24.39%,泌尿道占14.63%;检出病原菌38株,检出率为92.69%,其中,革兰阳性菌17株占44.74%,革兰阴性菌13株占34.21%,真菌5株占13.16%;通过对感染的相关因素进行分析,其中年龄、住院时间、低蛋白血症和侵入性操作等是导致皮肌炎患者发生感染的主要因素,差异有统计学意义(P<0.05)。结论皮肌炎患者感染的发生率高,应当针对相关因素采取合理措施,以有效预防其感染的发生,促进患者早日康复。
Objective To investigate the characteristics and related risk factors of combined infection in patients with dermatomyositis. Methods A retrospective analysis of 107 patients with clinical data and infection, and fill in a self-made form, including sex, age, length of stay, the patient’s infection rate, the site of infection, underlying diseases, pathogens, etc., and the use of epidemiological methods Statistical Analysis. Results There were 41 cases of nosocomial dermatomyositis with infection rate of 38.32%. Most of the infections were respiratory tract, accounting for 41.46%, followed by mucocutaneous infection, accounting for 24.39% and urinary tract accounting for 14.63%. 38 strains of pathogens were detected, Among them, 17 strains of Gram-positive bacteria accounted for 44.74%, 13 strains of Gram-negative bacteria accounted for 34.21% and 5 strains of fungi accounted for 13.16%. According to the analysis of related factors of infection, including age, hospitalization time, low Proteomics and invasive procedures were the main factors that led to the infection of dermatomyositis patients, the difference was statistically significant (P <0.05). Conclusion The incidence of dermatomyositis infection is high. Reasonable measures should be taken for the related factors to effectively prevent the occurrence of infection and promote the early recovery of patients.