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目的 :探讨门脉高压性胃病 (PHG )与幽门螺杆菌 (Hp)感染的关系及临床意义。方法 :对204例肝硬化患者进行了胃镜检查和Hp 测定。结果 :在伴有和不伴有PHG的肝硬化门脉高压患者的Hp 感染率差异无显著性 (P>0 05) ,不同程度的PHG患者Hp 感染率差异亦无显著性 (P>0 05)。门脉高压患者的Hp 感染率非常显著低于慢性胃炎组 (P<0 01)显著低于功能性消化不良 (FD )组 (P<0 05)。结论 :肝硬化门脉高压性胃病的Hp 感染率降低 ,可能与肝硬化患者胃内环境不适合Hp 的生存有关
Objective: To investigate the relationship and clinical significance between portal hypertensive gastropathy (PHG) and Helicobacter pylori (Hp) infection. Methods: 204 cases of liver cirrhosis patients underwent gastroscopy and Hp determination. Results: There was no significant difference in Hp infection rates between patients with and without PHG (P> 0.05). There was no significant difference in Hp infection rates among PHG patients (P> 0.05) ). The incidence of Hp infection in patients with portal hypertension was significantly lower than that in chronic gastritis group (P <0.01) and significantly lower than that in functional dyspepsia group (P <0.05). Conclusion: The incidence of Hp infection in cirrhotic patients with portal hypertensive gastropathy is decreased, which may be related to the unfavorable gastric environment in patients with liver cirrhosis