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脑白质疏松症(Leukoaraiosis,LA)是加拿大神经学家Hachinski等[1]于1987年首先提出的一个影像学术语,用于描述半卵圆中心及侧脑室区脑白质的弥散性斑片状或斑点状改变,临床发现LA的病例逐渐增多;而诊断LA最可靠的影像学诊断方法是扩散张呈成像DTI,DTI是一项新的影像学技术,不仅能够诊断出常规的MRI诊断LA部位,而且还可以诊断出常规的MRI无法诊断的早期LA部位,如患者头部的海马部、胼胝体部出现的脑白质损伤,DTI对于常规的MRI诊断LA的技术是一项有利的补充,可以为临床提供准确的诊断依据。1 LA的发病机制及病理基础LA可由多种疾病引起,如血管性痴呆、阿尔茨
Leukoaraiosis (LA) is an imaging term first proposed by Canadian neuroscientist Hachinski et al [1] in 1987 to describe the diffuse patchy form of white matter in the centrum semilunar and lateral ventricle regions or The change of spot shape has been found in LA patients. The most reliable diagnostic method for LA is diffusion imaging. DTI is a new imaging technique, which not only can diagnose the LA part by conventional MRI, But also can diagnose the early LA sites that can not be diagnosed by conventional MRI, such as white matter damage in the hippocampus and corpus callosum in the head of the patient. DTI is a good supplement to the routine MRI diagnosis of LA, which can be clinically Provide accurate diagnosis basis. 1 LA’s pathogenesis and pathology LA can be caused by a variety of diseases, such as vascular dementia, Alz