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钩端螺旋体病的传染和流行常给人类生命及畜牧业生产造成严重危害。我国曾发生过数十次大规模钩端螺旋体病流行。作为我国两个流行菌型之一的问号赖型钩端螺旋体在生物学特性和致病性有其独特性，但其遗传学特性和致病机制尚不完全清楚。为了探讨问号赖型钩端螺旋体抗原基因的?
Leptospirosis and epidemics often cause serious damage to human life and livestock production. There have been dozens of large-scale epidemics of leptospirosis in our country. As one of the two popular bacterial strains in China, Leptospira interrogans has its unique biological and pathogenicity, but its genetic characteristics and pathogenesis are not yet fully understood. In order to explore the question mark Leptospira antigen gene?