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应用马来丝虫易感媒介中华按蚊和不易感媒介淡色库蚊研究了丝虫对蚊虫不易感的机理，并进行了比较观察。９３％的马来微丝蚴不能穿过淡色库蚊胃壁，为其不易感染的主要原因，少数穿过胃壁的微丝蚴，在从血腔向胸肌的移行过程中被黑化反应杀死，构成其不易感的另一重要因素。
The mechanism of insecticide susceptibility of filariasis to mosquitoes was studied using the Malayi insect susceptible vector Anopheles sinensis and the susceptible vector Culex pipiens pallens. 93% of Malay microfilariae can not pass through the stomach wall of Culex pipiens pallens, which is the main reason that they are not easily infected. A few microfilariae that pass through the stomach wall are killed by melanization during the migration from the blood cavity to the pectoral muscle, Constitute another important factor of its not easy to feel.