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慢性阻塞性肺病(chronic obstructive pulmonary disease,COPD)是呼吸系统的常见病。各种内外因素作用导致气道、肺实质和肺血管的慢性炎症是COPD发病的关键机制。中性粒细胞、肺泡巨噬细胞、淋巴细胞等多种炎症细胞通过释放多种细胞因子而参与该慢性炎症的发生。本文对可能参与COPD炎症反应的细胞因子进行综述。
Chronic obstructive pulmonary disease (COPD) is a common respiratory disease. A variety of internal and external factors lead to chronic inflammation of the airways, lung parenchyma and pulmonary vascular disease is the key mechanism of COPD. Many inflammatory cells such as neutrophils, alveolar macrophages, and lymphocytes are involved in the occurrence of chronic inflammation by releasing various cytokines. This article reviews the cytokines that may be involved in the inflammatory response in COPD.