许多研究证明 ,肺动脉高压是非高原人进入高原发生急性高原病 (AHAD)的重要原因之一。一氧化氮 (NO)和内皮素 (ET)是一对血管舒缩因子 ,对肺动脉压的调节起着重要作用[1] ,故NO和ET的变化与快速进入高原者发生急性高原病有密切的关系 ,为了解快速进入高原者的血清NO和血浆ET变 Many studies have shown that pulmonary hypertension is one of the important reasons for non-altitude people to enter the plateau of acute high altitude disease (AHAD). Nitric oxide (NO) and endothelin (ET) are a pair of vasoconstrictors and play an important role in the regulation of pulmonary arterial pressure [1], so the changes of NO and ET are closely related to the rapid onset of altitude sickness In order to understand the rapid entry into the plateau of serum NO and plasma ET changes