虽然认为血小板内环腺苷磷酸(cAMP)和环鸟苷磷酸(cGMP)对血小板聚集起重要的作用,但对有关他们的磷酸二脂酶(PDE)的活性却很少了解。血小板功能在循环中受其环境、特别是血管壁内衬层的影响。作者曾报导在血栓栓塞性疾患急性期发生高聚集力,尤以肾上腺为引发剂 Although intracellular cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) are believed to play an important role in platelet aggregation, little is known about their phosphodiesterase (PDE) activity. Platelet function is influenced by its environment, especially the lining of the blood vessel wall, in the circulation. The authors have reported a high aggregation rate in the acute phase of thromboembolic disorders, especially the adrenal gland as an initiator