遗传性痉挛性截瘫与遗传性共济失调是一种罕见亚型。现将笔者所见四例报告如下。例1、男性,18岁。第五胎,患者从5岁始走路不稳,以后进行性加重,双下肢僵硬、以足尖着地走路摇幌,易跌跤。近二年来,吐字不清,偶有呛水现象来诊。父母非近亲婚配,兄妹共七人,其妹从4岁始,与患者症状相似。查体意识清,言语含糊。无眼震,咽反射正常。上肢肌力、肌张力、共济运动正常。双下肢肌力5°,肌张力增 Hereditary spastic paraplegia and hereditary ataxia is a rare subtype. Now I see the four cases reported below. Example 1, male, 18 years old. The fifth child, the patient started walking instability from the age of 5, after the progressive increase in stiffness, lower extremities, foot to foot shaking rocking, easy to fall. In the past two years, unclear articulation, occasionally choke water phenomenon diagnosis. Parents non-relatives of marriage, brother and sister a total of seven people, their sisters from the age of 4, similar to the symptoms of patients. Physical examination clear, vague language. Non-nystagmus, pharyngeal reflex normal. Upper limb muscle strength, muscle tone, mutual aid movement normal. Lower extremity muscle strength 5 °, muscle tension increased