镉(Cd)是自然环境中的一种重金属元素,随着人类进行矿石开采及金属冶炼等作业增加以及近年来工厂排污不规范,导致Cd污染发生的概率明显增高。Cd能导致肝、肾、骨骼、肺及听力的损伤,甚至引发癌症的发生。金属硫蛋白能与金属Cd相结合减弱Cd对机体脏器的毒性。因此了解金属硫蛋白在不同类型Cd中毒的表达具有重要意义。 Cadmium (Cd) is a heavy metal element in the natural environment. With the increase of human activities such as ore mining and metal smelting, as well as the non-standard discharge of pollutants from factories in recent years, the probability of Cd pollution is significantly increased. Cd can cause liver, kidney, bone, lung and hearing damage, and even lead to the occurrence of cancer. Metallothionein can combine with metal Cd to weaken the toxicity of cadmium to organ. Therefore, it is important to understand the expression of metallothionein in different types of Cd poisoning.