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了解胃幽门螺杆菌 (HP)感染对反流性食管炎治疗的影响。方法 :用双盲对照的方法对 12 6例反流性食管炎患者在用奥美拉唑治疗的同时 ,检测其胃中 HP的感染状态 ,试验结束后 ,根据其 HP的感染情况 ,将 12 6例患者分为 HP(+)组和 HP(- )组进行疗效对比。结果 :HP(+)组主要症状的缓解率高于 HP(- )组 (P<0 .0 5 )。 HP(+)组病变的治愈率在治疗后第 4周和第 8周分别为 75 %、88.5 % ;HP(- )组病变的治愈率在治疗后第 4周和第 8周分别为 6 2 .2 %、78.2 % ;两组相比差别有显著性。结论 :反流性食管炎患者用奥美拉唑治疗时伴有 HP感染者 ,其临床疗效比不伴有 HP感染者要好
To understand the influence of Helicobacter pylori (HP) infection on the treatment of reflux esophagitis. Methods: Twelve blind control patients were treated with omeprazole in 12 6 patients with reflux esophagitis. Meanwhile, the infection status of HP in the stomach was detected. After the test, according to the HP infection, 12 Six patients were divided into HP (+) group and HP (-) group for curative effect comparison. Results: The remission rate of main symptoms in HP (+) group was higher than that in HP (-) group (P <0.05). The cure rates of lesions in HP (+) group were 75% and 88.5% respectively at the 4th week and the 8th week after treatment. The cure rates of HP (-) group were 6 2 and 8 weeks after the treatment .2%, 78.2%; the difference between the two groups was significant. Conclusion: Reflux esophagitis patients treated with omeprazole with HP infection, the clinical efficacy than those without HP infection is better