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本文综合文献中428例系统性红斑狼疮(SLE)病例,有肝病实验室变化者可高达84.8%,24%有肝病的临床征候,58～66%的病例可找到引起肝病的肝外或肝内原因。对163例(占总数38%)有肝组织学检查的病例作综合分析,70%以上病例的肝组织学仅存在轻、中度的非特异性改变。肝功能试验中絮浊反应的阳性,与免疫球蛋白增高有关。系统性红斑狼疮本身并不引起明显肝损害。
In this paper, 428 cases of systemic lupus erythematosus (SLE) cases in the literature, with liver laboratory changes can be as high as 84.8%, 24% of clinical symptoms of liver disease, 58 to 66% of cases can be found in liver or liver disease caused by extrahepatic or intrahepatic the reason. A total of 163 cases (38% of the total) with histological examination of liver for a comprehensive analysis of more than 70% of cases of liver histology, there is only mild to moderate non-specific changes. Liver function test flocculation reaction positive, and immunoglobulin increased. Systemic lupus erythematosus itself does not cause significant liver damage.