肾上腺肿瘤可分为肾上腺皮质腺瘤、肾上腺皮质癌和肾上腺髓质肿瘤。80～90％的嗜铬细胞瘤起源于肾上腺髓质,其中恶变率为10％左右。一般的皮质癌因其瘤体体积大和高转移性易被诊断,然而大多数成年人所患的肾上腺肿瘤的良恶性,根据其内分泌指标和影像学特征往往难以鉴别。DNA的倍体分析技术曾被试图运用到肾上腺肿瘤的良恶性鉴别诊断上,但是进一步研究表明这种方法不够精确。因为不仅良性肿瘤细胞常有非整倍体DNA存在,而且癌细胞DNA也常表现整倍体。运用端粒重复 Adrenal tumors can be divided into adrenal cortical adenomas, adrenocortical carcinomas, and adrenal medulla tumors. 80 to 90% of pheochromocytoma originated in the adrenal medulla, which malignant transformation rate of about 10%. In general, cortical cancer is easily diagnosed because of its large volume and high metastasis. However, the benign and malignant tumors of adrenal glands that most adults suffer from are often difficult to discriminate based on their endocrine and imaging features. DNA ploidy analysis techniques have been tried in the differential diagnosis of benign and malignant adrenal tumors, but further studies have shown that this method is not accurate enough. This is because not only benign tumor cells often have aneuploid DNA, but also cancer cells often exhibit euploid DNA. Using telomere repetition