目的 :测定健康自愿受试者口服单剂量复安欣后的尿药浓度 ,同时与进口对照品进行比较。方法 :以八叠球菌作检定菌 ,采用生物效价方法进行抗菌活性测定。结果 :单剂量复安欣口服后 1～ 4 8h的尿药浓度与德国进口Monuril对照品比较 ,其高峰尿药浓度及维持时间均不低于该批进口样品 ,与文献报道的数据也基本相符。结论 :复安欣与进口产品相比 ,无论是生物效价 ,还是体内药物浓度均无差别 OBJECTIVE: To determine the concentration of urinary drug in healthy volunteers after oral single-dose Fu-Xin and compare with imported reference substance. Methods: The sarcina of Mycobacterium was used as the test bacteria, and the biological potency method was used to determine the antibacterial activity. Results: Compared with the imported Monuril reference substance from Germany, the peak urinary drug concentration and the maintenance time of single-dose Fufangxin 1 ~ 48h after oral administration were no lower than those of the imported samples, which were basically consistent with those reported in the literature . Conclusion: Compared with the imported products, Fu-Anxin had no difference in biological potency or in vivo drug concentration