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不孕不育治疗技术的广泛应用,使单卵双胎的发生率也随之增高。辅助生殖治疗中,促排卵药物的应用、透明带的损伤、胚胎培养条件、囊胚及多个胚胎移植均可导致单卵双胎的发生率明显高于自然妊娠,但具体的发生机制仍未明确,而且单卵双胎易导致双胎输血综合征等多种并发症,因此早期诊断、早期治疗对母婴预后有重要意义。近年,单卵双胎妊娠日渐受到生殖医学和产科医生的关注,现对辅助生殖治疗中影响单卵双胎发生的因素及其诊断、预后进行综述。
The wide application of infertility treatment technology, so that the incidence of monozygotic twins also increased. In assisted reproductive therapy, the application of ovulation induction drugs, the damage of zona pellucida, the conditions of embryo culture, blastocysts and multiple embryo transfer can lead to the significantly higher incidence of monozygotic twins than that of natural pregnancy, but the specific mechanism has not yet Clear, and monozygotic twins can easily lead to twin complications such as blood transfusion syndrome, early diagnosis and early treatment of maternal and child prognosis of great significance. In recent years, monozygotic twins pregnancy is increasingly concerned about by reproductive medicine and obstetricians, are now on the assisted reproductive treatment of monozygotic twins factors and diagnosis, prognosis are reviewed.