用干扰素治疗慢性丙型肝炎,约15％～25％的病人可取得所谓远期痊愈,肝硬化和肝细胞性肝癌的危险可能得到扭转。因此,无应答的可能性显著大于取得疗效,不同地区大约有50％～60％的慢性丙型肝炎病人经过3个月或6个月的干扰素治疗,不能获得疗效,或者只有生化缓解,另外20％～30％病人的病毒复制仅一过性受到抑制。因此特别是青年人和(或)伴有高度炎症活动性的病人存在着如何继续治疗的问题。 Interferon treatment of chronic hepatitis C, about 15% to 25% of patients get so-called long-term recovery, liver cirrhosis and hepatocellular carcinoma risk may be reversed. Therefore, the probability of non-response is significantly greater than the effect achieved, about 50% to 60% of patients with chronic hepatitis C in different regions after 3 months or 6 months of interferon therapy, can not be effective, or only biochemical relief, the other 20% to 30% of patients with viral replication was transiently inhibited. Therefore, there is a problem of how to continue the treatment especially for young people and / or patients with high inflammatory activity.