通过对随机取样的１２８例男性不育症患者的染色体分析，表明１４．４８％的不育症患者有染色体异常，这其中约９０％睾丸体积小，７０％第二性征发育不良，说明染色体异常对生精功能、睾丸及第二性征发育都有影响。文章还分析了Ｋｌｉｎｅｆｅｌｔｅｒ＇ｓ综合征、４６，ＸＸ女性性反转综合征、罗氏易位、常染色体易位、大Ｙ染色体异常等导致不育症的机制和预后，说明染色体检查在婚检中的重要意义。 Chromosomal analysis of 128 randomly selected male infertility patients showed that 14.48% of infertile patients had chromosomal abnormalities. About 90% of them had small testes and 70% of secondary sexual signs, indicating that chromosomes Abnormal spermatogenic function, testicular and secondary sexual development have an impact. The article also analyzes the mechanism and prognosis of Klinefelter’s syndrome, 46, XX female sexual inversion syndrome, Roche translocation, autosomal translocation, large Y chromosome abnormalities and other causes of infertility, indicating that chromosome examination in premarital Significance.