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目的观察重症脓毒症合并应激性心肌病患者采用连续性血液净化治疗的临床疗效。方法选取医院确诊治疗的重症脓毒症合并应激性心肌病患者120例作为研究对象,随机分为观察组和对照组,每组60例。对照组采取常规治疗,观察组在常规治疗基础上采取连续性血液净化治疗,比较2组临床治疗总有效率和不良反应发生情况。结果经治疗,观察组总有效率为90.0%,高于对照组的65.0%(P<0.05);观察组不良反应发生率为23.3%,低于对照组的50.0%(P<0.05)。结论重症脓毒症合并应激性心肌病患者采取常规治疗联合连续性血液净化治疗,效果显著,安全性高,值得在临床推广应用。
Objective To observe the clinical efficacy of continuous blood purification in patients with severe sepsis and stress cardiomyopathy. Methods A total of 120 patients with severe sepsis and stress cardiomyopathy who were diagnosed and treated in hospital were selected as study subjects and randomly divided into observation group and control group with 60 cases in each group. The control group to take conventional treatment, the observation group on the basis of conventional treatment to take a continuous blood purification treatment, the clinical efficacy of the two groups were compared and the incidence of adverse reactions. Results After treatment, the total effective rate in the observation group was 90.0%, higher than 65.0% in the control group (P <0.05). The incidence of adverse reactions in the observation group was 23.3%, which was lower than that in the control group (50.0%, P <0.05). Conclusion Severe sepsis patients with stress cardiomyopathy treated by conventional therapy combined with continuous blood purification, the effect is significant, high safety, it is worth in the clinical application.