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目的分析探讨中药坤灵丸在应用促排卵药物后有效预防卵巢过度刺激综合征(OHSS)的作用机制。方法 86例因排卵功能障碍而引起的不孕症患者,随机分为中药组和对照组,各43例。对照组患者采用口服氯米芬促排方案,中药组患者在对照组基础上加入中药坤灵丸治疗。分析对比两组患者的OHSS发生率以及妊娠率。结果中药组OHSS发生率显著低于对照组,差异有统计学意义(P<0.05);在3个月促排卵中,中药组的临床妊娠率高于对照组,差异有统计学意义(P<0.05)。结论坤灵丸在应用促排卵药物后能有效的预防OHSS的发生。
Objective To analyze and discuss the mechanism of traditional Chinese medicine Kun Ling Pills in preventing ovarian hyperstimulation syndrome (OHSS) after ovulation induction. Methods 86 cases of infertility caused by ovulation dysfunction were randomly divided into traditional Chinese medicine group and control group, 43 cases in each. Patients in the control group were treated with oral clomiphene, and patients in the TCM group were treated with Kun Ling pill in the control group. Analysis and comparison of two groups of patients OHSS incidence and pregnancy rate. Results The incidence of OHSS in the TCM group was significantly lower than that in the control group (P <0.05). The clinical pregnancy rate was significantly higher in the TCM group than in the control group at 3 months of ovulation induction (P < 0.05). Conclusion Kun Ling pill in the application of ovulation induction drugs can effectively prevent the occurrence of OHSS.