本文应用人血栓调节蛋白进行蛋白C功能检测,观察蛋白C在体外活化过程中血栓调节蛋白、蛋白C和凝血酶三者间的相互关系。人血栓调节蛋白在体外与凝血酶形成复合物而加速蛋白C的活化,牛凝血酶比人凝血酶对人血栓调节蛋白有更强的亲和性。血栓调节蛋白与凝血酶在蛋白C活化的作用中均呈现饱和性。本文就钙离子和肝素对体外蛋白C活化的影响及其生理意义进行了初步探讨。 In this paper, human thrombomodulin protein C function detection, protein C in vitro activation of thrombomodulin, protein C and thrombin in the relationship between the three. Human thrombomodulin accelerates the activation of protein C by forming a complex with thrombin in vitro, and bovine thrombin has a stronger affinity for human thrombomodulin than human thrombin. Thrombomodulin and thrombin saturate during protein C activation. This article on calcium and heparin on protein C activation in vitro and its physiological significance of a preliminary study.