系统性红斑狼疮(SLE)是全身多系统受累的自身免疫性疫病。以往认为受累器官常见于皮肤、关节、肾脏、心血管和胸膜等。近年来发现神经系统合并症并不少见,约占 SLE 的20～60%,是引起死亡和残废的主要原因。现介绍如下。1.癫痫:为本病神经系统合并症最主要症状之一,发病率5～57%。发作类型有大发作、小发作、 Systemic lupus erythematosus (SLE) is a systemic autoimmune disease involving multiple systems. In the past that affected organs common in the skin, joints, kidneys, cardiovascular and pleural. In recent years found that nervous system complications are not uncommon, accounting for 20 to 60% of SLE, is the leading cause of death and disability. Now introduced as follows. 1. Epilepsy: This disease is one of the most important symptoms of nervous system complications, the incidence of 5 to 57%. Types of seizures have a major episode, a minor episode,