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目的：探讨正电子发射断层扫描（ＰＥＴ） 葡萄糖代谢功能显像在癫癎灶定位诊断中的价值及其与脑电图（ＥＥＧ） 对癫癎灶定位的一致性。方法：５２０ 例ＭＲ 检查正常的癫癎病人，经动态脑电图（ＡＥＥＧ） 和ＰＥＴ检查定位，比较两者的一致性。结果：ＰＥＴ 定位的阳性率为９４－６ ％ ，ＡＥＥＧ 为５４ ％ ，除外ＥＥＧ 定位阴性的２３９ 例，二种定位检查结果完全一致４７－７ ％ （１３４／２８１） ，部分一致占２３－１ ％ （６５／２８１） ，完全不一致者占２９－２ ％ （８２／２８１） 。４ 例皮质脑电图（ＥＣｏＧ） 证实局灶性癫癎样放电与ＰＥＴ 检出的葡萄糖代谢减低区完全一致。结论：ＰＥＴ 是诊断癫癎灶灵敏而有效的方法，对癫癎病灶的定位价值优于ＥＥＧ、ＭＲ、ＣＴ和ＳＰＥＣＴ。
Objective: To investigate the value of functional imaging of positron emission tomography (PET) in the localization of epileptic foci and its consistency with the location of epileptic foci by electroencephalography (EEG). Methods: One hundred and fifty-two patients with normal epilepsy were examined by dynamic electroencephalography (EEG) and PET, and their consistency was compared. Results: The positive rate of PET localization was 94-6% and AEEG was 54%, except for 239 cases with negative EEG localization. The results of the two kinds of localization examination were completely consistent with 47-7% (134/281), and the partial agreement was 23-1% (65/281), completely inconsistent accounted for 29-2% (82/281). Four cases of cortical electroencephalography (ECoG) confirmed that focal epileptiform discharges were consistent with PET-detected areas of reduced glucose metabolism. Conclusion: PET is a sensitive and effective method for the diagnosis of epilepsy. The localization of epilepsy is superior to that of EEG, MR, CT and SPECT.