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目的探讨聚丙烯酰胺水凝胶治疗压力性尿失禁(SUI)的疗效。方法回顾性分析2005年10月至2010年8月德国开姆尼茨红十字中心医院应用聚丙烯酰胺水凝胶经尿道注射治疗压力性尿失禁患者450例,追踪381例术后的主观效果和客观效果。结果术后患者的主观评价结果显示SUI的治愈率和好转率之和为76.4%,客观评价结果显示SUI的治愈率和好转率之和为83.2%,无严重并发症发生。结论经尿道注射聚丙烯酰胺水凝胶治疗压力性尿失禁具有安全、简便、疗效确切、并发症少、患者可接受性高等优点,有望成为女性SUI的重要治疗方法,但仍需长期随访。
Objective To investigate the therapeutic effect of polyacrylamide hydrogel on stress urinary incontinence (SUI). Methods A retrospective analysis of 450 patients with stress urinary incontinence treated with polyacrylamide hydrogel at the Chemnitz Red Cross Central Hospital in Germany from October 2005 to August 2010 followed up 381 subjective outcomes Objective effect. Results The postoperative patients’ subjective evaluation showed that the cure rate and improvement rate of SUI were 76.4%. The objective evaluation showed that the sum of cure rate and improvement rate of SUI was 83.2% without serious complications. Conclusion Transurethral injection of polyacrylamide hydrogel in the treatment of stress urinary incontinence is safe, simple, effective, with fewer complications and patients with high acceptability. It is expected to be an important treatment for SUI in women. However, long-term follow-up is still needed.