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我们观察了26例原发性肾病综合征(NS)患者在不同病理类型下的血脂和载脂蛋白(apo)水平变化,旨在探讨肾脏的病理因素与NS的高脂血症和apo异常的关系。 一、资料与方法 1.病例:选择原发性NS患者26例,其中男18例,女8例,年龄平均27.9±5.4岁,无肾功能不全,无并发症和其它疾病,未用皮质激素、利尿剂、β-受体阻滞剂等影响脂质代谢的药物。患者均接受肾活检,病理结果如下:微小病变(MCD)10例,非微小病变(n-MCD)16例.其中局灶性肾小球硬化4例,系膜增殖性
We observed the changes of blood lipid and apolipoprotein (apo) levels in 26 patients with idiopathic nephrotic syndrome (NS) under different pathological types to explore the relationship between renal pathological factors and hyperlipidemia and abnormal apo relationship. First, the data and methods 1. Case: 26 patients were selected primary NS patients, including 18 males and 8 females, mean age 27.9 ± 5.4 years, no renal insufficiency, no complications and other diseases, no corticosteroids , Diuretics, β-blockers and other drugs that affect lipid metabolism. The patients underwent renal biopsy and the pathological results were as follows: 10 cases of minimal change (MCD) and 16 cases of non-minimal change (n-MCD), including 4 cases of focal glomerulosclerosis,