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目的人巨细胞病毒pp65蛋白(HCMV pp65)抗原血症检测已被认为是预测活动性感染非常好的指标。但临床医生对移植患者此项检查的最佳时机掌握并不十分准确。本文拟探讨HCMV pp65抗原移植患者阳性率、移植术后HCMV pp65抗原检测的最佳时期。方法①回顾性分析100例次HCMV pp65抗原检测,计算阳性率。②对10例HCMV pp65阳性患者,计算初次阳性出现时期例数分布情况。结果①移植患者术后HCMV pp65抗原阳性率为10.O%;②HCMV pp65抗原术后检测出现阳性时期集中在术后第一至三个月,此后极少。结论①肾移植患者术后HCMV pp65抗原阳性率为10.O%。②术后第一至三个月患者易感HCMV,为HCMV pp65抗原高密度检测最佳时期,第四个月至1年可低密度监测。
The detection of antigenemia of the target human cytomegalovirus pp65 protein (HCMV pp65) has been considered as a very good predictor of active infection. However, it is not very accurate for clinicians to grasp the optimal timing of this test for transplant patients. This paper intends to explore the positive rate of HCMV pp65 antigen transplantation, HCMV pp65 antigen after transplantation the best period of detection. Methods ① A retrospective analysis of 100 cases of HCMV pp65 antigen test, calculate the positive rate. ② For 10 cases of HCMV pp65-positive patients, the distribution of the number of cases with initial positive appearance was calculated. Results ① The positive rate of HCMV pp65 antigen in patients after transplantation was 10.O%; ②HCMV pp65 antigen positive after surgery was found in the first to third months after operation, and very few thereafter. Conclusions ① The positive rate of HCMV pp65 antigen in renal transplant recipients was 10. O%. ② The first to third months post-operative patients were susceptible to HCMV, which was the best time for high-density detection of HCMV pp65 antigen, and could be monitored for low density from the fourth month to the first year.