乳腺癌是女性最常见的恶性肿瘤之一,多发于欧美国家,在我国尤其是经济发达地区其发病也呈上升趋势,在许多大中城市,乳腺癌已占妇女恶性肿瘤死因的首位,严重威胁着妇女的健康。近年来对乳腺癌高发家族的分析表明,存在一个或更多的常染色体显性乳腺癌易感基因,所有乳腺癌中5%￣10 Breast cancer is one of the most common malignant tumors in women and occurs frequently in Europe and the United States. Its incidence is also on the rise in our country, especially in economically developed areas. In many large and medium-sized cities, breast cancer has taken the first place in the cause of death of malignant tumors among women, which is a serious threat Women’s health. In recent years, high incidence of breast cancer family analysis shows that there is one or more autosomal dominant breast cancer susceptibility genes, all breast cancer 5% ~ 10