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外科手术切除可谓根治大肠癌的唯一疗法。但有时既使施行了手术,也难免复发。因此,有必要于手术后追加辅助治疗。常用方法为术后化疗,但迄今尚无特效药物及可靠的给药方法。近年多采用多剂并用化疗。通常用于大肠癌的化疗药物有代谢抑制剂5-FU,UFT,HCFU,5’-DFUR、Ara-C等;氮芥类药物CPA,CQ,ACNU等;以及抗生素类药物MMC等。治疗中除选择药物外,给药方法也是非常
Surgical resection is the only cure for colorectal cancer. However, sometimes surgery is performed and recurrence is inevitable. Therefore, it is necessary to add supplementary treatment after surgery. The commonly used method is postoperative chemotherapy, but there are no specific drugs and reliable methods of administration. In recent years, multiple doses of chemotherapy have been used. Chemotherapy drugs commonly used for colorectal cancer include metabolic inhibitors 5-FU, UFT, HCFU, 5’-DFUR, Ara-C, etc.; nitrogen mustard drugs CPA, CQ, ACNU, etc.; and antibiotics such as MMC. In addition to the choice of drugs in the treatment, the method of administration is also very