主动脉缩窄(coarctation of the aorta,CoA)占所有先天性心脏病的5%~10%。20世纪40年代中期以来,手术治疗CoA已成为可能,但术后高血压及左心室肥厚(left ventricular hypertrophy,LVH)等并发症仍困扰着患者。高血压是CoA患者术后最常见的并发症,发生率25%~68%,其中巨大差异与不同的高血压诊断标准、研究人群及诊断方法有关。另外,高血压与CoA患者术后的早期死亡有关。多达70%的CoA病例涉及二叶式主动脉瓣,常 Coarctation of the aorta (CoA) accounts for 5% to 10% of all congenital heart disease. Surgical treatment of CoA has been possible since the mid-1940s, but complications such as postoperative hypertension and left ventricular hypertrophy (LVH) continue to plague patients. Hypertension is the most common postoperative complications of CoA, the incidence of 25% to 68%, of which huge differences with different diagnostic criteria for hypertension, study population and diagnostic methods. In addition, hypertension is associated with early postoperative mortality in CoA patients. Up to 70% of cases of CoA involve the bifocal aortic valve, often