肠粘膜固有层浆细胞分泌入肠腔的ＩｇＡ对维持局部抗体的有效水平，拮抗细菌定植、粘附，以及中和肠腔毒素等方面均起重要作用；另一方面，肠道菌群对ＩｇＡ的分泌又起诱导作用〔１〕。但有关肠粘膜固有层浆细胞的数量及分布，在不同肠道菌群背景小鼠中的变化，尚未见报道。因 Intestinal mucosal lamina propria cells secreted into the intestine of IgA to maintain the effective level of local antibodies to antagonize bacterial colonization, adhesion, and intestinal and toxin play an important role; the other hand, intestinal flora on IgA The secretion of induction and play 〔1〕. However, the number and distribution of plasma cells in the lamina propria of the intestinal mucosa have not been reported in mice with different gut microbiota background. because