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报告36例肺癌患者(腺癌14、鳞癌14、小细胞未分化癌8),212例肺感染患者(肺结核12、肺炎9),4例志愿者的BLF及40例正常人和上述三组的SLF放射免疫测定值。结果:SLF:肺癌组均值4.78μg/ml,显著高于正常组1.18μg/ml(p<0.05),但与感染组均值1.69μg/ml比较无差异;BLF:肺癌组均值53.95μg/ml,显著高于正常组4.05μg/ml及肺感染组15.44μg/ml(p<0.01)。如以20μg/ml为界值,肺癌组敏感性为67%,特异性86%。对腺癌敏感性为86%.可作为周围型肺癌早期诊断的参考。
Reported 36 patients with lung cancer (adenocarcinoma 14, squamous cell carcinoma 14, and small cell undifferentiated carcinoma 8), 212 patients with pulmonary infection (tuberculosis 12, pneumonia 9), 4 volunteers with BLF and 40 normal subjects and the above three groups SLF radioimmunoassay values. Results: The average value of SLF: lung cancer group was 4.78μg/ml, which was significantly higher than that of normal group (1.18μg/ml) (p<0.05), but there was no difference between the average value 1.69μg/ml of the infection group and the mean value of BLF: lung cancer group 53.95μg/ml. Significantly higher than the normal group 4.05μg/ml and lung infection group 15.44μg/ml (p<0.01). With a cutoff of 20 μg/ml, the lung cancer group had a sensitivity of 67% and a specificity of 86%. The sensitivity to adenocarcinoma is 86%. Can be used as a reference for early diagnosis of peripheral lung cancer.