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钚-239是一种物理半衰期为24000年的α粒子放射体,若因吸入或刺伤而进入体内就会牢固地存留,除非用治疗措施以促使其排出。Bukhtoyarova等曾以每公斤体重2μCi硝酸钚-239注射给两性刚成年的Wistar大鼠,每天治疗DTPA用量约为500μmol/kg。结果表明,注射~(239)Pu的组,发现骨肉瘤为12/62=19±5％,第1天开始DTPA治疗的组为3/58=5±3％,1月开始治疗的组为5/61=8±4％,1年开始治疗的为
Beta-239 is an alpha particle emitter with a physical half-life of 24,000 years. If it enters the body through inhalation or stab wounds, it will remain firmly in place unless treatment is used to promote its excretion. Bukhtoyarova et al. had once injected adult sexual Wistar rats with 2 μCi of bismuth nitrate-239 per kilogram body weight, and the daily dose of DTPA was about 500 μmol/kg. The results showed that in the group injected with ~(239)Pu, 12/62=19±5% of osteosarcoma was found, and 3/58=5±3% of the group treated with DTPA on the first day. The group that started treatment in January was 5/61 = 8 ± 4%, starting at 1 year