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目的:系统评价中西医结合预防腹部术后肠梗阻的临床疗效,为腹部术后患者在术后恢复阶段的治疗提供参考和依据。方法:计算机检索CNKI期刊全文数据库、万方数据库、维普中文科技期刊数据库、Pubmed、Cochrane数据库中关于中西医结合预防腹部术后肠梗阻临床试验。检索时限从2000年7月—2015年7月,提取的相关数据采用Revman 5.2软件进行统计分析。结果:最终纳入随机对照试验9项共2430例患者。Meta分析显示中西医结合预防腹部术后肠梗阻总体效果明显优于西医常规治疗[OR=0.20,95%可信区间(0.14,0.29),P<0.00001]。中西医结合治疗在改善腹部术后第一次排气时间临床效果上亦优于西医常规治疗[SMD=-5.70,95%可信区间(-9.23,-2.17),P=0.002<0.05]。结论:术后患者结合临床尽早给予中西医结合治疗可促进其胃肠功能的恢复及减少术后肠梗阻的发生,大大加快了患者身体的康复速度。但是由于纳入试验的研究方法有待改进以及文献质量不高,所以需要更多的随机对照研究加以证实。
OBJECTIVE: To systematically evaluate the clinical efficacy of integrated traditional Chinese and western medicine in preventing postoperative intestinal obstruction, and to provide a reference and basis for the treatment of postoperative recovery in patients with abdominal surgery. Methods: A computerized clinical trial of CNKI integrated traditional Chinese and western medicine in prevention of postoperative intestinal obstruction was retrieved from CNKI full-text database, Wanfang database, VIP Chinese scientific journal database, Pubmed, Cochrane database. Retrieval time from July 2000 to July 2015, the extracted data using Revman 5.2 software for statistical analysis. Results: A total of 2430 randomized controlled trials were included in 9 items. Meta-analysis showed that the overall effect of TCM-WM combination in preventing postoperative intestinal obstruction was significantly better than that of western medicine [OR = 0.20, 95% confidence interval (0.14, 0.29), P <0.00001]. Integrative treatment of abdominal gas in improving the first time after the clinical efficacy of exhaust time is also superior to conventional Western medicine [SMD = -5.70,95% confidence interval (-9.23, -2.17), P = 0.002 <0.05]. Conclusion: Postoperative patients combined with clinical early treatment with Integrative Medicine can promote the recovery of gastrointestinal function and reduce the incidence of postoperative intestinal obstruction, greatly speeding up the recovery of the patient’s body. However, due to the improved methods of research into the trials and the poor quality of the literature, more randomized controlled studies are needed to confirm this.