灵芝菌丝体超氧化物歧化酶（ＳＯＤ）同工酶谱带有５条，其中酶带Ⅰ，Ⅳ，Ⅴ为Ｍｎ—ＳＯＤ，酶带Ⅱ，Ⅲ为Ｃｕ—Ｚｎ—ＳＯＤ。Ｃｕ—Ｚｎ—ＳＯＤ在不同浓度的ＫＣＮ作用下，其活力随ＫＣＮ的浓度增大而逐渐丧失，而Ｍｎ—ＳＯＤ不受ＫＣＮ影响仍具催化活性；Ｃｕ—Ｚｎ—ＳＯＤ在氯仿—乙醇的作用下仍具催化活性，而Ｍｎ—ＳＯＤ随氯仿—乙醇的浓度增大而失去活力；ＳＤＳ可使Ｍｎ—ＳＯＤ失去活性，但对Ｃｕ—Ｚｎ—ＳＯＤ无影响；β—巯基乙醇使部分Ｃｕ—Ｚｎ—ＳＯＤ失去活性，但对Ｍｎ—ＳＯＤ无影响。 Ganoderma lucidum mycelium superoxide dismutase (SOD) isozyme bands with 5, of which I, IV, V Mn-SOD, enzyme bands Ⅱ, Ⅲ Cu-Zn-SOD. The activity of Cu-Zn-SOD gradually decreased with the increase of KCN concentration under the different concentration of KCN, while the catalytic activity of Mn-SOD was not affected by KCN. Under the action of chloroform-ethanol, Cu-Zn- But Mn-SOD lost its vitality with the increase of chloroform-ethanol concentration; SDS could deactivate Mn-SOD, but had no effect on Cu-Zn-SOD; β-mercaptoethanol caused part of Cu-Zn- SOD lost its activity but had no effect on Mn-SOD.